Download Calcified Tissues 1965: Proceedings of the Third European by L. F. Bélanger, T. Semba, S. Tolnai, D. H. Copp, L. Krook, PDF

By L. F. Bélanger, T. Semba, S. Tolnai, D. H. Copp, L. Krook, C. Gries (auth.), H. Fleisch, H. J. J. Blackwood, M. Owen (eds.)

ISBN-10: 3642858430

ISBN-13: 9783642858437

The papers accrued during this quantity signify the formal court cases of the 3rd eu Symposium on Calcified Tissues which was once held in Davos, Switzerland from eleventh to sixteenth April 1965 lower than the sponsorship of the Laboratorium fur experi­ mentelle Chirurgie, Schweizerisches Forschungsinstitut Davos. This Symposium fol­ lowed the now validated culture of the former Symposia held in Oxford in 1963 and in Liege in 1964. Participation was once back strictly on a residential foundation. This yr the Schatz alp inn supplied a scenic and secluded assembly position excessive on a mountain aspect overlooking Davos but as regards to the Forschungsinstitut within which the outlet consultation of the Symposium used to be held. The papers and communications released within the quantity are prepared so as of presentation and are grouped below the 5 major subject matters chosen for dialogue by way of the Symposium, specifically, "Cell functionality within the formation, upkeep and destruc­ tion of osseous tissue", "Response of calcified tissues to mechanical factors", "Mecha­ nisms of mineralization and ailments on the topic of mineral deposition", "Hormones and bone" and "Fundamental constitution of dental demanding tissues". The programme consisted of a few evaluation lectures given via invited audio system and of brief communications when it comes to all of the above issues. No try used to be made to list the dis­ cussions to the papers as, being a residential assembly, the extra priceless and curiosity­ ing interchanges happened informally in small chat groups and never in the time time table of the prearranged programme.

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Extra info for Calcified Tissues 1965: Proceedings of the Third European Symposium on Calcified Tissues held at Davos (Switzerland), April 11th–16th, 1965

Example text

After hydrolysis in 6 N Hel, the amount of hydroxyproline was measured and this amino acid purified by thin layer chromatography in the presence of cold carrier. The radioactivity of the samples was measured in a liquid scintillation counter. The results are illustrated in Table 2 for different time points up to 48 hours. A. aM. A. of the hydroxyproline of the un fractionated bone. This method of computing the data allows us to locate the migration of the label. The only variable is the time elapsed since the synthesis of the collagen.

Until recently, little has been known about the way collagen is synthesized and degraded in bone while some progress has been made in the last few years concerning these processes in soft connective tissues. This difference in the amount of information is mainly due to the difficulty in applying to calcified tissues the temniques of investigation used for the study of collagen metabolism in soft connective tissues. There is, however, no reason to think that the main steps of formation and removal of the collagen fibers are completely different in bone compared to soft collagenous structures.

After 17 days of cultivation hypertrophic cartilage cells were formed and alongside this zone a border of bone was deposited (Fig. 2). From these experiments it is obvious that the donor tissue has indeed the potency to form bone. However, this result does not prove that in grafts the donor tissue also produces bone. In order to get some information on this point donor cells were made distinguishable from host cells by labelling the donor tissue with 3H-thymidine prior to transplantation; in this way the fate of the donor cells during their presence in the host could be determined.

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