By Lijie Grace Zhang, John P Fisher, Kam Leong
3D Bioprinting and Nanotechnology in Tissue Engineering offers a detailed advent to those applied sciences and their commercial functions. Stem cells in tissue regeneration are coated, besides nanobiomaterials. Commercialization, criminal and regulatory concerns also are mentioned on the way to assist you translate nanotechnology and 3D printing-based items to and the health facility. Dr. Zhang’s and Dr. Fishers’ group of specialist individuals have pooled their services so as to supply a precis of the suitability, sustainability and barriers of every process for every particular software. The expanding availability and lowering expenses of nanotechnologies and 3D printing applied sciences are using their use to fulfill scientific wishes, and this ebook presents an summary of those applied sciences and their integration. It indicates how nanotechnology can raise the medical potency of prosthesis or synthetic tissues made by means of bioprinting or biofabrication. scholars and pros will obtain a balanced evaluation of appropriate know-how with theoretical starting place, whereas nonetheless studying concerning the latest printing techniques.
- Includes medical functions, regulatory hurdles, and risk-benefit research of every technology.
- This publication will help you in choosing the right fabrics and making a choice on the ideal parameters for printing, plus comprise cells and biologically lively brokers right into a published constitution
- Learn some great benefits of integrating 3D printing and nanotechnology with a view to enhance the security of your nano-scale fabrics for biomedical applications
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Extra info for 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
2008). The types of hydrogels utilized for structure fabrication using light-assisted bioprinting include, but are not limited to, poly(ethylene glycol) diacrylate (PEGDA), poly(ethylene glycol) dimethacrylate (PEGDMA), methacrylamide-modified gelatin (GelMOD), gelatin methacrylate (GelMA), and glycidyl methacrylate modified hyaluronic acid (GMHA). , 2014). PEGDA hydrogels, with their superior biocompatibility, high water retention ability, and tunable mechanical properties, in particular stiffness retention, serve as excellent candidates for synthetic 36 CHAPTER 2 3D Printing and Nanomanufacturing b iomaterials for biomedical applications (Baroli, 2007).
Biofabrication 3, 034102. , 2013. Carbon-nanotubeembedded hydrogel sheets for engineering cardiac constructs and bioactuators. ACS Nano 7, 2369–2380. , 2004. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303, 1352–1355. , 2008. Suturereinforced electrospun polydioxanone-elastin small-diameter tubes for use in vascular tissue engineering: a feasibility study. Acta Biomater 4, 58–66. , 2010. A three-dimensional bioprinting system for use with a hydrogel-based biomaterial and printing parameter characterization.
The glass transition temperature and viscosity of PPF and 40 CHAPTER 2 3D Printing and Nanomanufacturing DEF mixture resin is dependent on the weight ratio of PPF and DEF. Glass transition temperature drops dramatically by adding DEF. , 2007). Different ranges of laser parameters and resin compositions were employed to analyze the effects on the properties of scaffolds. Considering viscosity and mechanical properties, PPF/DEF mixtures with a 60:40 weight ratio and 1% BAPO might be optimal. 4 CELLS AND BIOAPPLICATIONS Light-assisted biomanufacturing techniques have been used to fabricate tissue constructs with various types of cells and applications.